Feminizing HRT Timeline and Effects

While the degree to which an individual taking feminising hormone therapy will experience changes varies from person to person, the following table provides an indication of the HRT timeline.

MTF HRT effect timeline

Effects Expected Onset Expected Maximum Effect
Body fat redistribution 3-6 months 2-5 years
Decreased muscle/mass strength 3-6 months 1-2 years
Softening of skin/decreased oiliness 3-6 months unknown
Decreased libido 1-3 months 1-2 years
Decreased spontaneous erections 1-3 months 3-6 months
Male sexual dysfunction variable variable
Breast growth 3-6 months 2-3 years
Decreased testicular volume 3-6 months 2-3 years
Decreased sperm production variable variable
Thinning and slowed growth of body and facial hair 6-12 months >3 years
Male pattern baldness No regrowth, loss stops 1-3 months 1-2 years

The degree and rate of physical effects depend in part on the dose, route of administration, and medications used, which are selected in accordance with a patient’s specific medical goals (e.g., changes in gender role expression, plans for sex reassignment) and medical risk profile.

There is no current evidence that response to hormone therapy – with the possible exception of voice deepening in trans masculine individuals – can be reliably predicted based on age, body habitus, ethnicity, or family appearance. All other factors being equal, there is no evidence to suggest that any medically approved type or method of administering hormones is more effective than any other in producing the desired physical changes.

Source: https://www.gendergp.com/hrt-timelines-hormones-effects/